From Caltech
Part of the scenario sounds as if it could have leaped from a book by Dr. Oliver Sacks. Call it the Case of the Lady Who Got Uncomfortably Close. "SM", in fact, was a patient who had suffered extensive damage to her amygdala, a part of the brain known as the "seat of emotion." She had a habit, those who knew her well discovered, of being too friendly and getting uncomfortably close. She invaded folks' "personal space." And from that observation of human behavior sprang experiments that have led researchers to decide that, independent of sensory clues (sounds, sights, smells), the amygdala regulates social distance. Cultural factors may help humans learn to adjust their sense of social distance, say in places where space is more at a premium. But the findings about where social distance gets regulated may be key to autism research; the complex neurodevelopmental disorder manifests with an inability to interact socially and to communicate with others. Besides her over friendly approach to personal space, patient SM, like some with autism, has difficulty recognizing fear in others' faces and in judging others' trustworthiness.
